Comparative Effects of Neural Mobilization and Myofascial Release Technique on Pain, Range of Motion and Disability Among Patients With Post Lumbar Spine Fusion
DOI:
https://doi.org/10.68279/5vzvny74Keywords:
Lumbar spine fusion; Neural mobilization; Myofascial release; Stabilization exercises; Low back pain; DisabilityAbstract
Background: Persistent pain and functional disability may continue following lumbar spine fusion and require postoperative rehabilitation. Neural mobilization and myofascial release target different potential contributors to persistent symptoms, but their comparative effects remain uncertain. Objective: To compare neural mobilization with myofascial release, each combined with stabilization exercises, for reducing pain and disability following lumbar spine fusion. Methods: This randomized clinical trial included 34 participants recruited through convenience sampling from clinical settings in Hyderabad, Sindh, Pakistan, and allocated equally to two groups. Group A received neural mobilization plus stabilization exercises, whereas Group B received myofascial release plus stabilization exercises. Both groups additionally received TENS and hot-pack application three times weekly for six weeks. Pain and disability were assessed using the Numeric Pain Rating Scale (NPRS) and Oswestry Disability Index (ODI) at baseline and Week 6. Paired- and independent-samples t-tests were used for analysis. Results: NPRS decreased from 6.30±1.20 to 2.80±1.00 in Group A and from 6.10±1.30 to 3.60±1.10 in Group B. ODI decreased from 42.50±6.80% to 18.60±5.40% and from 41.90±7.10% to 24.20±6.00%, respectively. At Week 6, Group A had lower NPRS (mean difference −0.80; 95% CI −1.53 to −0.07; p=0.034) and ODI scores (−5.60 percentage points; 95% CI −9.59 to −1.61; p=0.007). Conclusion: Both rehabilitation approaches were associated with short-term reductions in pain and disability, with greater improvement observed in the neural mobilization group
References
1. Reisener MJ, Pumberger M, Shue J, Girardi FP, Hughes AP. Trends in lumbar spinal fusion—a literature review. J Spine Surg. 2020;6(4):752-61. doi:10.21037/jss-20-492.
2. Sebaaly A, Lahoud MJ, Rizkallah M, Kreichati G, Kharrat K. Etiology, evaluation, and treatment of failed back surgery syndrome. Asian Spine J. 2018;12(3):574-85. doi:10.4184/asj.2018.12.3.574.
3. Cho KJ, Suk SI, Park SR, Kim JH, Kim SS, Choi WK, et al. Complications in posterior fusion and instrumentation for degenerative lumbar scoliosis. Spine (Phila Pa 1976). 2007;32(20):2232-7.
4. Madera M, Brady J, Deily S, McGinty T, Moroz L, Singh D, et al. The role of physical therapy and rehabilitation after lumbar fusion surgery for degenerative disease: a systematic review. J Neurosurg Spine. 2017;26(6):694-704. doi:10.3171/2016.10.SPINE16627.
5. Sawyer K. The impact of spinal stabilization exercises on pain, disability, and physical function after lumbar spinal fusion [dissertation]. Texas Woman's University; 2019.
6. Lin LH, Lin TY, Chang KV, Wu WT, Özçakar L. Neural mobilization for reducing pain and disability in patients with lumbar radiculopathy: a systematic review and meta-analysis. Life (Basel). 2023;13(12):2255. doi:10.3390/life13122255.
7. Basson A, Olivier B, Ellis R, Coppieters M, Stewart A, Mudzi W. The effectiveness of neural mobilization for neuromusculoskeletal conditions: a systematic review and meta-analysis. J Orthop Sports Phys Ther. 2017;47(9):593-615. doi:10.2519/jospt.2017.7117.
8. Baptista FM, Nery E, Cruz EB, Afreixo V, Silva AG. Effectiveness of neural mobilisation on pain intensity, functional status, and physical performance in adults with musculoskeletal pain: a systematic review with meta-analysis. Clin Rehabil. 2024;38(2):145-83. doi:10.1177/02692155231215216.
9. Zhao P, Lu Z, Zou H, Wang J, He Y, Li M, et al. Effectiveness of myofascial release combined with capacitive-resistive therapy in patients with chronic nonspecific low back pain: a randomized controlled trial. Pain Res Manag. 2025;2025:9309502. doi:10.1155/prm/9309502.
10. Bittencourt JV, Corrêa LA, Pagnez MAM, do Rio JPM, Telles GF, Mathieson S, et al. Neural mobilisation effects in nerve function and nerve structure of patients with peripheral neuropathic pain: a systematic review with meta-analysis. PLoS One. 2024;19(11). doi:10.1371/journal.pone.0313025.
11. Boff TA, Pasinato F, Ben AJ, Bosmans JE, van Tulder M, Carregaro RL. Effectiveness of spinal manipulation and myofascial release compared with spinal manipulation alone on health-related outcomes in individuals with non-specific low back pain: randomized controlled trial. Physiotherapy. 2020;107:71-80. doi:10.1016/j.physio.2019.11.002.
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Muhammad Qasim, Fariha Ambreen, Muhammad Zeeshan, Noorjhan, Muhammad Talha, Areeba Ghouri (Author)

This work is licensed under a Creative Commons Attribution 4.0 International License.